The Decline Of Tissue Regenerative Potential Is A Hallmark Of Ageing And May Be Due To Age-Related Changes In Tissue-Specific Stem Cells

mitali nagwanshi

Abstract


Notably, hetero chronic Para biopsies restored the activation of Notch signaling as well as the proliferation and regenerative capacity of aged satellite cells. The exposure of satellite cells from old mice to young serum enhanced the expression of the Notch ligand (Delta), increased Notch activation, and enhanced proliferation in vitro.

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References


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